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Most effective clinical options include: Hydroquinone (4%) remains the gold standard to treat hyperpigmentation Q-switched lasers break down melanin deposits effectively Chemical peels with specific acids remove pigmented layers Newer treatments like tranexamic acid and cysteamine cream have fewer side effects Can home remedies really reduce melanin levels

A recent study showed that PUFA-enriched neurons under ferroptotic stress are more likely to trigger lipid peroxidation (LPO) and structural disruption in adjacent endothelial cells

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doi: 10.1016/j.actbio.2014.06.015