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For instance, network-based analyses of a Danshen (Salvia) multi-component formula identified nine key compounds collectively modulating 42 cardiovascular-related genes, highlighting how a mixtures efficacy arises from multi-target synergy (Li et al., 2011)

GAC1 was also the one of 15 compounds isolated and identified from Ganoderma lucidum , upon being identified as the extract responsible for inhibition of TNF- production by murine macrophages [110]