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Testing whether a peptide was primarily present in a modified or unmodified state We also sought to detect PTMs that systematically differed in abundance from their unmodified peptides within fresh and stored RBCs
Meyer EB, Wells WW
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Tricyclic NNMT inhibitors (e.g., Ruf 2022 series) occupy different binding modes and scaffolds used primarily in drug-discovery lead optimisation
Lysyl oxidase (LOX)mediated collagen cross-linking further increases ECM rigidity, which in turn activates integrinFAKYAP/TAZ and Wnt/-catenin signaling pathways, and promotes epithelialmesenchymal transition (EMT) and fibrogenesis (126)
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