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The value is greater route precision, but the tradeoff is injection training, sterile handling, and follow-up monitoring

Importantly, the first committed step of the pathway, catalyzed by glucose-6-phosphate dehydrogenase (G6PD), is inhibited by NADPH [57]

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This was a very small pilot study of 20 women that observed a 33% reduction in fibroid volume and a 48% reduction in uterine volume over the course of 6 months. These results suggest that DMPA may shrink fibroids, however this is a very early, low-quality evidence by pharmaceutical standards