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Tirzepatide, however, activates both the GLP-1 receptor and a second hormone pathway called glucose-dependent insulinotropic polypeptide (GIP), producing greater improvements in insulin sensitivity, weight loss and metabolic inflammation

In rodent studies, GLP-1 medications caused thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

By increasing insulin production when your blood sugar is high and reducing the amount of sugar your liver releases, semaglutide helps keep your blood sugar levels within a healthier range, which reduces your appetite and improves your quality of life

These are some of the most common side effects people experience when starting tirzepatide

Insurance coverage for weight management medications varies considerably among plans