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Regulation and metabolic significance of de novo lipogenesis in adipose tissues

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PLP-dependent enzymes have been classified into five structural classes known as Fold Type I-V (5): Fold Type I - aspartate aminotransferase family Fold Type II - tryptophan synthase family Fold Type III - alanine racemase family Fold Type IV - D-amino acid aminotransferase family Fold Type V - glycogen phosphorylase family The many biochemical reactions catalyzed by PLP-dependent enzymes are involved in essential biological processes, such as hemoglobin and amino acid biosynthesis, as well as fatty acid metabolism

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