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CVD: Cardiovascular Disease Although several in-line GLP-1 and glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RAs have approved indications beyond T2D and overweight/ obesity, US Pharmacopeia Drug Classification (USP DC) 2025 limits classification to categories/classes according to their primary diagnosis (e.g., antidiabetic

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doi: 10.1016/j.ejphar.2018.03.024 237 LiCLiuWLiXZhangZQiHLiuSet al