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Deficiency symptoms include fatigue, pale or slightly yellowing skin, shortness of breath, palpitations, diarrhoea, tingling in fingers and toes, and lack of coordination

High quality clinical trials are needed to prove its efficacy as a skin whitener, its dose, how long its effect lasts, and what types of pigmentation it can work well on.3

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However, in comparison with placebo or basal insulin, tirzepatide increased odds of nausea, while the doses of 10 and 15 mg were also more likely to cause vomiting or diarrhoea