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This isn't a spike

The lack of effect of p28 on the level of TAp73 in p53 mut triple negative MDA-MB-231 and normal MCF10A cells, and increase in Np73 in the same cells suggested that TAp73 and Np73 were regulated independently of p53 with cell and tissue type(s) being a dominant factor

Liver X receptor- gene expression is positively regulated by thyroid hormone

[1] Endocrine Axis Models: Used in laboratory models to explore growth hormone axis regulation under controlled experimental conditions

Metabolites with P -values 0.05 and variable importance in projection (VIP) 1 in the difference were considered as biomarkers [21]