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They may also recommend GLP-1s to individuals who are at increased risk for cardiovascular disease, since some studies show these medications can help protect heart health
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GLP-1 agonists like semaglutide (Ozempic) act primarily on metabolic and interoceptive systemstargeting hypothalamus, brainstem, and nucleus tractus solitariusbut they also modulate reward circuitry, including the nucleus accumbens and ventral tegmental area
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15 Furthermore, while non-autoimmune multinodular toxic goiter was found to be the primary cause of hyperthyroidism in a low iodine region of Denmark, Graves disease was still nearly as common in this region as it was in a high iodine region of Iceland, underlining the importance of sufficient but not excessive iodine intake
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