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Muco-penetrating approaches that have made it to the clinic include PEGylated adrenomedullin (NCT04417036, phase II of BAY1097761 for acute respiratory distress syndrome), amikacin liposomes (FDA-approved for mycobacterium infections therapy) and ciprofloxacin liposomes (NCT02104245, phase III of ciprofloxacin liposomes for non-cystic fibrosis bronchiectasis), all showing better penetration and retention in the airways during delivery (Table 3)

[15-17] While the new study published recently in 2023 adds to the knowledge base, it's a study published in 2019 that provides the most valuable insight explaining what we meant by the phrase anti-diabetic up above

doi: 10.3389/fnut.2019.00146 40