Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood
[DOI] [PubMed] [Google Scholar] 115.Butler C.C., Vidal-Alaball J., Cannings-John R., McCaddon A., Hood K., Papaioannou A., McDowell I., Goringe A
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However, there is a small problem with being able to achieve this through supplementation: synthetic forms are poorly bioavailable , that is, the body cannot take advantage of them in its processes, and thus the benefits of external supply are negated
Non-diabetic obese: the loudest instrument Non-diabetic obesity provides the clearest weight-loss estimate