By activating both GIP and GLP-1 receptors, tirzepatide enhances glucose-dependent insulin secretion from pancreatic beta cells, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying
Coskun, T., et al
Vu TT, Marquez J, Le LT, Nguyen ATT, Kim HK, Han J
A single Wegovy pen typically costs between $540 and $570 without insurance, which breaks down to approximately $400-$529 per month depending on your prescribed dose. For context, Health Canadas Drug Agency estimates annual Wegovy treatment at the list price costs approximately $5,066 per patient per year (roughly $420 per month) based on the recommended maintenance dose of 2.4 mg weekly. Current Promotional Pricing: Novo Nordisk offers a Wegovy Savings Program where self-pay patients can reduce costs to $149 per month for the 1.5 mg and 4 mg doses through April 15, 2026 (offer available for eligible patients only)
According to the PICOS (Population, Intervention, Comparison, Outcome and Study Design) principles, a literature search was conducted in conjunction with the following MeSH and keywords: For population: diabetes mellitus OR diabetes OR diabetic