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Clinical trials of brand-name semaglutide showed an average of 15% weight loss plus reduced cardiovascular risk in patients with metabolic syndrome these studies inform how the active ingredient is understood, but the safety, efficacy, and quality data from those trials do not directly apply to compounded preparations

Rosenstock J, Kim SW, Baron MA, Camisasca RP, Cressier F, Couturier A, Dejager S

The trials enrolled thousands of adults with obesity or overweight with weight-related health conditions across multiple countries and ran for 68 weeks

Mayo, F

We hypothesize that GLP-1 receptor activation may inhibit pro-inflammatory mediators, which are elevated in people with psoriasis, Ludwig said