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To overcome ROS-induced damage, both the host and pathogen developed antioxidant systems to quench excess ROS (Barna et al., Botrytis cinerea , causing the gray mold disease of plants (Veloso and van Kan, 2018)

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Furthermore, NADPH is replenished by the isocitrate dehydrogenase (IDH1/IDH2) branch of the citric acid cycle (TCA cycle), malic enzyme (ME1), and one-carbon metabolism (such as the folate cycle) depending on cell type or nutritional status

[DOI] [PubMed] [Google Scholar] 44.Gruber J., Chen C.B., Fong S., Ng L.F., Teo E., Halliwell B

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