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There is no reliable way to predict individual response before initiating treatment, making therapeutic trials necessary

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However, as the definition of IC/BPS appears to be expanding from a bladder disease to a chronic pain syndrome, reliable new outcome measures will have to be developed

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Publication trends of research on sepsis and host immune response during 1999-2019: a 20-year bibliometric analysis

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The mechanism may involve metalloproteinases (MMPs)

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But over time, research tells us that that gap narrows

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