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Diphenhydramine also interacts with the acetylcholine receptor where the word cholinergic is derived in the brain, where the vomiting hub sits, making it useful to treat motion sickness and nausea

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Gastrointestinal Side Effects Gastrointestinal side effects are common in the short term

Compounded medications may be legally prepared and dispensed under applicable state and federal pharmacy law, but they are not FDA-approved, and FDA does not verify compounded drugs for safety, effectiveness, or quality before marketing