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Given that obesity is a hallmark of BBS and a significant driver of its associated comorbidities, a deepening understanding of BBS5s role in metabolism could yield critical insights into disease pathogenesis

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2c) but it is notable that the inhibitory effect of GLP-1(736) (10 pmol/l) was reduced by exendin(939), indicating that part of GLP-1(736)s action is mediated by GLP-1R (possibly via stimulation of somatostatin secretion

doi: 10.1016/j.tem.2020.02.009 111 SerranoJBTabelingNCde Winter-KorverCMvan DaalenSKMvan PeltAMMMulderCL