PMID: 12499241
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Liraglutide (GLP1-agonist) showed no significant maternal to fetal transfer at least 3.5 hours after maternal exposure in a human study with one subject
For example, for a variety of diseases, including chronic obstructive pulmonary disease, osteoarthritis, joint stiffness and diabetic nephropathy (Yagishita et al., 2019)
Increased expression of TIPE1 in DKD leads to the ubiquitinated degradation of PHB2, which disturbs mitochondrial homeostasis, inhibits PINK1/Parkin-mediated mitochondrial autophagy, and encourages EMT and kidney damage