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In a 2014 article published in Molecular Therapy , author Michelangelo Campanella noted that a particular peptide showed the ability to increase testosterone production

Additional risk factors include advancing age (due to reduced gastric acid production), excessive alcohol consumption (impairing absorption and storage), and rare genetic disorders affecting B12 transport or metabolism

However, to the best of our knowledge, no randomized feeding trial so far has formally tested the effects of isocaloric protein restriction (PR) on circulating levels of IGF-1 and IGF binding proteins in men with localized prostate cancer who might benefit the most from a sustained reduction in IGF-1 levels