Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide receptor agonists Tirzepatide is a once-weekly, subcutaneous injectable peptide with dual agonist activity at both GLP-1 and GIP receptors
Cellular zinc metabolism in autoimmune diseases Zinc plays various roles in autoimmune diseases, including its function as an effector of the immune system, inflammation, and metabolism
Astrocytes, oligodendrocytes, and microglia, as well as other cell types, collectively make up the adult brain and spinal cord
Together these signs are called hypoketotic hypoglycemia
Conclusion: We describe a protocol generating SC-islets with adult-like cytoarchitecture and glucose sensitivity, engaging the triggering pathway and the neurohormonal and metabolic amplifying pathways of insulin secretion