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The reviews analysis confirms that synthetic GLP-1 medications like semaglutide and tirzepatide, originally developed to control blood sugar, offer clinically validated protection against cardiovascular disease (CVD), chronic kidney disease (CKD), and metabolic dysfunction-associated steatotic liver disease (MASLD)-related outcomes, including improvements in steatosis and fibrosis-related endpoints

9 Conclusions and future directions Evidence synthesized in this review indicates that Erastin has potential to control EMS by exploiting lesion-specific vulnerabilities in iron handling and redox balance