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Della Flora E, Perera CL, Cameron AL, Maddern GJ

For instance, the observed mitigation of microgliosis and pro-inflammatory cytokine release could be directly investigated by co-culturing our hCiPSC-NSCs or their conditioned medium with activated microglial cells (e.g., BV-2 cell line or primary microglia stimulated with LPS/ATP)

In addition to the correlation analysis above, in order to substantiate the conclusions further, a confirmatory 6 stage hierarchical linear regression model was built to predict Glu levels from GABA concentrations, while controlling for Group (OCD vs HV) and Voxel (OCC, ACC and SMA regions)