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Efficacy endpoints were analyzed using the full analysis set (all randomized participants according to the intention-to-treat principle)

Kazi reported grants from the National Heart, Lung, and Blood Institute, American Heart Institute, Agency for Healthcare Research and Quality, Patient-Centered Outcomes Research Institute, and Institute for Clinical and Economic Research outside the submitted work

This is not about willpower or discipline

It also increases insulin production in the pancreas in a dose dependent manner

"FDA Approves First Treatment to Reduce Risk of Serious Heart Problems Specifically in Adults with Obesity or Overweight"