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Novo Nordisk agonist shows strong trial results as MASH cases rise among US adults For the first time, a GLP-1 therapy has been cleared to treat metabolic dysfunction-associated steatohepatitis (MASH), after the US Food and Drug Administration (FDA) granted accelerated approval to Novo Nordisks weight-loss drug Wegovy

"Wegovy is blunting the dopamine hit from drinking

Neuroprotective & Mitochondrial Studies GH and IGF-1 have demonstrated neuroprotective and mitochondrial support roles , suggesting potential utility for investigating neurodegenerative and aging-related processes [Frohman 2000]

Apoe + macrophages can also reduce pulmonary fibrosis directly via phagocytosis of Collagen I, which depended on the increased glycolysis and LPR1 binding 56