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Only 8% of the total cohort were low early responders, and of those, just 23% eventually reached 15% total weight loss

Gut Microbes 11 , 16081631 (2020)

John Wilding, professor of medicine in the Department of Cardiovascular and Metabolic Medicine at the University of Liverpool, said this was unsurprising, adding: Obesity is a chronic disease that usually relapses when treatment is stopped. Tricia Tan, professor of metabolic medicine, diabetes and endocrinology at Imperial College London/Imperial College Healthcare NHS Trust, said: There is increasing evidence that structured exercise is important to prevent weight regain after cessation of weight-loss drugs, but noted that this was not discussed in the study

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