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We devised a set of four double mutants, one of which showed cell surface expression, detected by fluorescently labelled Nb1_gbHSV (Extended Data Fig

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Thus, the plasma level of reduced glutathione even after administration in high doses is insignificant (C max in plasma, 1 nmol / ml 5 min after administration of 600 mg), while cysteine metabolite levels are higher (C max in blood plasma 17 nmol / ml)