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Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species

Circulation, 106 (20), 25302532

However, recent studies suggest that combining lactate-targeting methods, including MCT4 inhibitors, with immunotherapy may offer new treatment options

But ultimately, the pancreas cant keep up, and blood sugar rises to levels that, 2 if left untreated, can lead to issues like skin complications, nerve damage, eye complications, and diabetic ketoacidosis