"I think these oral GLP-1s mean having more tools in our toolbox, having more options for different people who might react differently to different medicines," he said
Approximately 14% of the patients in this study were Hispanic
Semaglutide has been structurally modified to prevent it from being broken down by an enzyme in the blood called dipeptidyl peptidase-4 or DPP-4
When initial therapy proves insufficient, treatment escalation includes: Biologic DMARDs targeting specific inflammatory pathways (TNF inhibitors, IL-6 inhibitors, T-cell costimulation blockers, B-cell depleting agents) Targeted synthetic DMARDs such as JAK inhibitors (tofacitinib, baricitinib, upadacitinib), which carry FDA boxed warnings for serious cardiovascular events, malignancy, and thrombosis [24] [25] Combination DMARD therapy Short-term glucocorticoids for symptom control during treatment initiation Before starting biologic or targeted synthetic DMARDs, screening for tuberculosis and hepatitis B is recommended, along with appropriate vaccinations according to ACR guidelines
Towards an engaged urban pedagogy
