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Your body has to convert it before it can be used, and many of the patients who walk in saying Ive taken B12 for years and never felt anything turn out to have been on cyanocobalamin the whole time

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Therapeutic strategies to deplete macrophages in atherosclerotic plaques

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Classically activated M1 microglia, induced by stimuli such as lipopolysaccharide (LPS) and interferon-gamma (IFN- ), release neurotoxic cytokines including IL-1 and tumor necrosis factor alpha (TNF- )