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Neuropharmacology 129, 4756

The signaling pathway involving STAT3/Nrf2/GPX4 is integral to the resistance observed in osteosarcoma cells and may serve as a promising therapeutic target to improve the effectiveness of cisplatin against bone tumors ( Figure 6 ) (191)

Phytic acid is considered an antioxidant due to its property of inhibiting hydroxyl radical formation, by chelating free iron, and making it unavailable for free radical formation

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