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And this is the most important point it is not a substitute to a healthy lifestyle

The natural aging process plays the most significant role in this process

Its regulation both at a genetic level (both transcriptional and translational) and a biochemical level (post-translational) is incredibly complex

The key anti-oxidative transcription factor, nuclear factor E2 related factor 2 (Nrf2 or NFE2L2), plays a dominant role in defense machinery by reprogramming the iron, intermediate, and glutathione peroxidase 4 (GPX4)-related network and the antioxidant system to attenuate ferroptosis

In conclusion, our findings provide evidence that GLP-1R expression is associated with a reduced risk of ENOC, partially mediated through its effects on body weight and lipid metabolism