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The commentary accompanying the original paper highlighted these results as evidence that senescent cell elimination could produce systemic rejuvenation rather than isolated organ-specific improvements (Krimpenfort & Berns, 2017)

Exenatide twice daily: a review of its use in the management of patients with type 2 diabetes mellitus

Furthermore, carvedilol has been shown to exert cytoprotective effects against ROS generation in the liver, indicating its antioxidant properties (Ronsein et al., 2005)

18 , e3000680 (2020)

After that, everything goes through your liver for processing, which can further reduce the amount of nutrients that actually make it to your cells