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Results Semaglutide-induced weight loss results from reduced food consumption in ob/ob mice Eight-week-old male and female ob/ob mice were maintained on a standard chow diet for four weeks where their average body weight reached 50g and 52g for male and female respectively, after which they were treated with either 3 nmol/kg semaglutide or vehicle for three weeks (Figure 1A) and the food and body weight recorded daily

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[25] [66] The US Food and Drug Administration (FDA) approved semaglutide based on evidence from seven clinical trials of 4087 participants with type 2 diabetes