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Off-Label Use on the Rise Despite the promising data, many of these potential benefits fall outside the current FDA-approved uses, which include obesity, Type 2 diabetes, cardiovascular risk reduction, and more recently sleep apnea in some cases

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These side effects are typically mild to moderate but can sometimes be severe

A Waters Symmetry reverse-phase C18 column (2.1 mm 150 mm, 3.5 m) was used for the LC separation as described ( 8 and PGB 2 ] were monitored