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Some things to think about include: The type of cancer being treated The specific chemotherapy agents used The presence of any gastrointestinal symptoms that may affect B12 absorption Managing Pre-existing B12 Deficiency During Treatment Patients with B12 deficiency before treatment need special care

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The reactive oxygen species then donates one electron to a glutathione molecule, completing the oxidation-reduction reaction and rendering it unable to perform oxidative damage to the cell