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2024;38(S3):311

Its mechanisms of action have been primarily explored in non-clinical studies involving animal models, cell cultures, and limited human cohorts

Hence, the likelihood of concomitant use of kratom with other psychoactive substances like opioids, benzodiazepines, or antidepressants is high

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Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat