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R 1 is H, or R 1 represents 1 to 3 substituents selected from halo, nitro, carboxylate or a derivative thereof, cyano, hydroxyl, alkyl, haloalkyl, alkoxy, haloalkoxy, and OR 6 , where R 6 is hydrogen or optionally substituted aryl, a phenol protecting group, a prodrug moiety, alkyl, arylalkyl, C(0)R 7 , P(0)(OR 8 ) 2 , or S0 3 R 8 , where R 7 and R 8 are independently selected in each instance from H, alkyl, alkenyl, cycloalkyl, heterocyclyl, aryl, and arylalkyl, each of which is optionally substituted, or R is a metal cation

Vrang N, Phifer CB, Corkern MM, et al

doi: 10.1016/j.bcp.2021.114723

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