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Seminal ROS levels, DNA fragmentation indices, and antioxidant enzyme profiles (e.g., SOD, GPx) can guide the selection and dosing of antioxidants

In context of this review, it is interesting to note that studies have shown that silencing the GSTA4 (GST alpha) gene results in mitochondrial dysfunction, as is also seen in GSTA4 null mice, which could contribute to insulin resistance in type 2 diabetes [97]

However, autoimmune patients often take immunosuppressive medications that may interact with GLP-1 therapy in ways that have not been fully studied

Current Treatment Options Managing PCOS typically involves a multifaceted approach aimed at addressing the various symptoms and underlying issues

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