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In a sucrose-fed rat model, where animals developed significantly lower aortic tissue glutathione and higher aortic tissue oxidised glutathione (GSSG) compared with controls, 1 % v/v GLY offered in drinking water for 4 weeks restored glutathione levels in vascular tissue and significantly reduced markers of oxidative damage

Progress in vesicular formulations, including ultra-deformable liposomes (transfersomes and ethosomes), has enhanced skin permeability by allowing the vesicles to go across intercellular routes in the stratum corneum under osmotic gradients or ethanol-induced lipid fluidisation [258, 281]

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