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For example, some secreted biosurfactants like homologue of outer membrane protein A from bacteria Pantoea spp

Collectively, four converging mechanismsBMP-SMAD activation, PI3K/FOXO3 modulation, angiogenic remodelling and redox homeostasisexplain how PD-MSCs and their engineered derivatives revive endocrine and reproductive competence, setting the stage for precision stem-cell or secretome therapies that are both effective and minimally invasive

In this case peptide therapy IS largely considered to be safe but I just wanted to point out that simply because something is naturally occurring shouldnt automatically make you think its safe

10.1016/j.freeradbiomed.2022.06.004 28 IngoldI.BerndtC.SchmittS.DollS.PoschmannG.BudayK.et al (2018)