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The study included a total of 111 randomized patients: placebo (26), tirzepatide 12 mg (29), tirzepatide 15 mg-1 (28), and tirzepatide 15 mg-2 (28)

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Abbreviations GLP-1RAs: Glucagon-like peptide-1 receptor agonists AF: Atrial fibrillation GWAS: Genome-wide association study cis-eQTLs: cis-expression quantitative trait loci OR: Odds ratio CI: Confidence interval T2DM: Type 2 diabetes mellitus MR: Mendelian randomization SNPs: Single nucleotide polymorphisms RCTs: Randomized clinical trials BMI: Body mass index ICD: International Classification of Diseases IVW: Inverse-variance weighted MR-PRESSO: Mendelian Randomization Pleiotropy RESidual Sum and Outlier MVMR: Multivariable Mendelian randomization PP.H4: Posterior probability of hypothesis 4 CAD: Coronary artery disease References Rawshani A, Rawshani A, Franzn S, Eliasson B, Svensson AM, Miftaraj M, et al