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Signs of B12 deficiency: Oral B12 supplements require absorption through the gastrointestinal tract

Normal saline (0.9% sodium chloride) can cause peptide precipitation with some formulations

Louis, MO, United States), 40 g/ml Proline (Sigma-Aldrich), 50 g/ml ascorbic acid (Sigma-Aldrich) and 10 ng/ml TGF-1 (Peprotech, Rocky Hill, NJ, United States)

Factors That Affect How Long B12 Injections Last Several factors may influence how long the effects of a B12 injection last in your system, potentially explaining why some patients require more frequent injections than others, even with the same underlying condition

Reilly and Mak, 2012