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In previous clinical trials, semaglutide has demonstrated significant reductions in MACE, including CV-related death, non-fatal myocardial infarction, and non-fatal stroke [38,39,40, 42,43,44,45]

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Cells with the morphological appearance of MCs - aligned and located in the MCL and with a diameter of at least 20 m - were labelled by FLEX, as well as scattered smaller cells within the GCL

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