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Interestingly, we transfected 293T cells with Myc-labeled ubiquitin, HA-labeled KEAP1, and Flag-labeled NRF2 plasmids and observed that the upregulation of KEAP1 promoted the poly-ubiquitination of NRF2, and SP could down-regulate the KEAP1 expression and block the NRF2 ubiquitination dose-dependently (Supplementary Fig

All statistical analyses were conducted on the TriNetX Advanced Analytics Platform

Available from: Wang H, Liu Z, Shao J, et al

Occasionally, there are hypercellular areas with slight cellular pleomorphism, features that may arouse suspicion of a low-grade myxoid sarcoma