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Such alignment may be one of the keys to unlocking vitality in our later years, helping us not only live longer, but live better

Recognition of receptor-mediated mitophagy depends on receptor proteins such as Atg32 in yeast (Okamoto et al., 2009) and several proteins in mammals, including NIP3-like protein X (Novak et al., 2010), Bcl-2 19-kDa interacting protein 3 (Zhu et al., 2013), FUN14 domain containing 1 (Liu et al., 2012), FK506-binding protein 8 (Bhujabal et al., 2017), and Bcl2-like 13 (Murakawa et al., 2015)

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This is where stress hijacks appetite becomes relevant, because cortisol-driven stress loops can weaken satiety signaling and increase reward-based eating patterns