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Liraglutide could reduce monthly migraine days Liraglutide, a glucagon-like peptide-1 receptor (GLP-1R) agonist used to treat diabetes, appears to reduce monthly migraine days by more than half, researchers reported on June 20, 2025 at the annual European Academy of Neurology (EAN) Congress 25

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Upon administration, Liraglutide mimics the activity of endogenous GLP-1, which is normally released by the intestines in response to food intake