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The starting dose of 1 mg is higher in absolute terms than semaglutide starting dose, but the relative potency is comparable

Longer lasting or more serious episodes can cause loss of consciousness or cardiac arrest, which can be life threatening

Groups for whom retatrutide may not be appropriate include: Those with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2): Rodent studies with GLP-1 receptor agonists have shown thyroid C-cell tumours

The review included six studies with 92 participants who had concomitant diagnoses of HS and obesity or diabetes

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