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Recently, a study reported that cyclic-di-adenosine monophosphate (c-di-AMP) in live gram-positive bacteria could interact with the innate sensor stimulator of interferon genes (STING) to mediate ER stress and induce mechanistic target of rapamycin (mTOR) inactivation, resulting in ER-phagy [62]

[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Gwyer D, Wragg NM, Wilson SL

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It is a remarkable act of self-organization, and it is also not a solution