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Prieto-Hontoria, P., et al., Impact of dietary lipoic acid supplementation on liver mitochondrial bioenergetics and oxidative status on normally fed Wistar rats

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L-NAME induces high blood pressure by acting as nitric oxide synthase (NOS) inhibitor ( 2 production and malondialdehyde (MDA) level in plasma and thoracic aorta and increased the level of SOD and CAT antioxidant enzymes, suggesting the potency of MO against oxidative stress-related hypertension in L-NAME rats ( via NOS-sGC dependent signaling

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